Morphologic changes in striatonigral neurons in a rat model of levodopa-induced dyskinesia

We aimed to elucidate morphological changes in striatonigral projection neurons in a rat model of levodopa-induced dyskinesia (LID). Male Wistar rats underwent unilateral 6-hydroxydopamine lesioning to establish a hemiparkinsonian model. At 8 weeks postoperatively, the rats were allocated to either...

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Principais autores:	Masako Fujita, Haruo Nishijima, Tomonori Furukawa, Fumiaki Mori, Aogi Kobayashi, Chieko Suzuki, Koichi Wakabayashi, Masahiko Tomiyama
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-10-01
Series:	Neuroscience Research
Assuntos:	Dendritic spine morphology GABAergic transmission Levodopa-induced dyskinesia Parkinson's disease Striatonigral projection neurons Substantia nigra pars reticulata
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0168010225001361
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