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Design, Synthesis and Biological Evaluation of New Carbohydrate-Based Coumarin Derivatives as Selective Carbonic Anhydrase IX Inhibitors via “Click” Reaction

In this work, we designed a series of new carbohydrate-based coumarin carbonic anhydrase IX inhibitors by using 1,2,3-triazoles as linker. Next, these designed compounds were synthesized by the optimized one-pot click chemistry reaction condition. Subsequently, these target compounds were assayed fo...

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Detalhes bibliográficos
Principais autores: Naying Chu, Yitong Wang, Hao Jia, Jie Han, Xiaoyi Wang, Zhuang Hou
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-08-01
coleção:Molecules
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Acesso em linha:https://www.mdpi.com/1420-3049/27/17/5464
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