Specific reversal agents for direct oral anticoagulants in neurosurgical emergencies – a systematic review

Background: Direct oral anticoagulants (DOACs) are widely used but pose significant challenges in emergency neurosurgical settings. Idarucizumab and andexanet alfa are approved reversal agents, yet their effectiveness and safety in neurosurgical emergencies remain unclear. Objectives: This systemati...

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Bibliografiska uppgifter
Huvudupphovsmän: Laura Zeller, Jonas Rohr, Giovanna Brandi, Christoph Globas, Alexander Kaserer, Matthias Greutmann, Tilman Schubert, Jan-Dirk Studt, Katharina Geiling, Luca Regli, Menno R. Germans
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2025-11-01
Serie:Research and Practice in Thrombosis and Haemostasis
Ämnen:
andexanet alfa
hemostasis in surgery
idarucizumab
neurosurgery
neurosurgical emergencies
oral anticoagulant reversal
Länkar:http://www.sciencedirect.com/science/article/pii/S2475037925005497
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