The Lipid Virulence Factors of <i>Mycobacterium tuberculosis </i>Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Autophagy is an important innate immune defense mechanism that controls <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>) growth inside macrophages. Autophagy machinery targets <i>Mtb</i>-containing phagosomes via xenophagy after damage to the phagosomal membrane due to the Type VII secretion system Es...

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Principais autores:	Aïcha Bah, Merlin Sanicas, Jérôme Nigou, Christophe Guilhot, Catherine Astarie-Dequeker, Isabelle Vergne
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-03-01
Serija:	Cells
Teme:	autophagy mycobacterium tuberculosis lipids macrophage phagosome lysosomes innate immunity
Online dostop:	https://www.mdpi.com/2073-4409/9/3/666
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