The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).

<h4>Background</h4>Apolipoprotein E is a glycoprotein best known as a mediator and regulator of lipid transport and uptake. The APOE-ε4 allele has long been associated with increased risks of Alzheimer's disease and mortality, but the effect of the less prevalent APOE-ε2 allele on diseases in the el...

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Principais autores:	Frank J Wolters, Qiong Yang, Mary L Biggs, Johanna Jakobsdottir, Shuo Li, Daniel S Evans, Joshua C Bis, Tamara B Harris, Ramachandran S Vasan, Nuno R Zilhao, Mohsen Ghanbari, M Arfan Ikram, Lenore Launer, Bruce M Psaty, Gregory J Tranah, Alexander M Kulminski, Vilmundur Gudnason, Sudha Seshadri, E2-CHARGE investigators
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2019-01-01
Series:	PLoS ONE
Acceso en liña:	https://doi.org/10.1371/journal.pone.0219668
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