Cold exposure increases aortic dissection risk through extracellular cold inducible RNA binding protein and toll like receptor 4 signaling

Abstract Several observational studies have indicated a greater risk of cardiovascular diseases in cold weather. Cold-inducible RNA-binding protein (CIRP) is highly conserved and upregulated in response to various cellular stressors. Although CIRP provides protective effects against cold exposure, e...

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Egile Nagusiak:	Hsiao-Ya Tsai, Wu-Chien Chien, Chi-Hsiang Chung, Chih-Yuan Lin, Yu-Juei Hsu, Min-Chien Tsai, Chin-Wang Hsu, Shih-Hung Tsai
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2026-03-01
Saila:	Scientific Reports
Gaiak:	Aortic dissection Aortic aneurysm Cold stress Cold inducible RNA binding protein Toll-like receptor-4 Matrix metalloproteinase
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-026-38164-9
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