Chemistry and Bioinformatics Considerations in Using Next-Generation Sequencing Technologies to Inferring HIV Proviral DNA Genome-Intactness

HIV persists via integration of the viral DNA into the human genome. The HIV DNA pool within an infected individual is a complex population that comprises both intact and defective viral genomes, each with a distinct integration site, in addition to a unique repertoire of viral quasi-species. Obtain...

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Hlavní autor:	Guinevere Q. Lee
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-09-01
Edice:	Viruses
Témata:	HIV genomes HIV persistence deep sequencing
On-line přístup:	https://www.mdpi.com/1999-4915/13/9/1874
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