Robust genome editing activity and the applications of enhanced miniature CRISPR-Cas12f1

Abstract With recent advancements in gene editing technology using the CRISPR/Cas system, there is a demand for more effective gene editors. A key factor facilitating efficient gene editing is effective CRISPR delivery into cells, which is known to be associated with the size of the CRISPR system. A...

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Hlavní autoři:	Soo-Ji Park, Sungjin Ju, Won Jun Jung, Tae Yeong Jeong, Da Eun Yoon, Jang Hyeon Lee, Jiyun Yang, Hojin Lee, Jungmin Choi, Hyeon Soo Kim, Kyoungmi Kim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-01-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-56048-w
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