Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena

Abstract Background INO80 and SWR1 are evolutionarily related ATP-dependent chromatin remodeling complexes that regulate the chromatin occupancy of the histone variant H2A.Z, playing critical roles in transcriptional regulation, genome replication, and DNA repair. While the H2A.Z-related functions o...

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Detalhes bibliográficos

Principais autores:	Jyoti Garg, Alejandro Saettone, Syed Nabeel-Shah, Steven Dang, Abdul Hadi Khalid, Jérémy Loehr, Alexandra Petrova, James D. Burns, Peter Karabatsos, Sherin Shibin, Suzanne Wahab, Sean D. Taverna, Jack F. Greenblatt, Jean-Philippe Lambert, Jeffrey Fillingham
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-08-01
coleção:	Epigenetics & Chromatin
Assuntos:	Bromodomains SWR1c INO80c H2A.Z Chromatin remodeling Transcription
Acesso em linha:	https://doi.org/10.1186/s13072-025-00614-5
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