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Effects of individualized PEEP titration on intraoperative cardiac output in thoracoscopic lung surgery: a prospective randomized trial

Abstract Personalized positive end-expiratory pressure (PEEP) based on pulmonary compliance may improve intraoperative hemodynamics and postoperative outcomes in thoracic surgery. This study aimed to evaluate the effect of individualized, compliance-guided PEEP titration on cardiac output (CO) and p...

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Main Authors: Mengyue Zhu, Tianhao Song, Qinyu Bao, Jing Wang, Jin Wang, Weiyi Wang, Zhenghuan Song, Jing Tan
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-03-01
Series:Scientific Reports
Subjects:
Cardiac output
Individualized PEEP
Thoracoscopic pulmonary resection
Hemodynamic parameters
One-lung ventilation
Online Access:https://doi.org/10.1038/s41598-026-43122-6
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