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A PRELIMINARY STUDY OF STEREOSELECTIVITY OF MEFLOQUINE ENANTIOMERS IN RAT

Stereoselectivity of mefloquine enantiomers were studied in rats after oral administration of a single 50mg/Kg dose of the racemate. Pharmacokinetic parameters of (+)-(RS)-MFQ in blood and plasma showed no significant difference. The concentration, AUC , CLIF and VdlF of (+)-(RS)-enantiomerin blood...

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主要な著者: E. Souri., H. Farsam F. Jamali
フォーマット: Artigo
言語:Inglês
出版事項: Tehran University of Medical Sciences 1998-12-01
シリーズ:Acta Medica Iranica
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オンライン・アクセス:https://acta.tums.ac.ir/index.php/acta/article/view/1758
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