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RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancer.

PURPOSE:Epithelial ovarian cancer has the highest mortality rate of all gynecological malignancies. We have shown that high RAN expression strongly correlates with high-grade and poor patient survival in epithelial ovarian cancer. However, as RAN is a small GTPase involved in two main biological fun...

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Autors principals: Katia Y Cáceres-Gorriti, Euridice Carmona, Véronique Barrès, Kurosh Rahimi, Isabelle J Létourneau, Patricia N Tonin, Diane Provencher, Anne-Marie Mes-Masson
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2014-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3953127?pdf=render
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