Improvement of Adeno-Associated Virus (AAV)-Based Technologies by Cell-Penetrating Penta-Peptides (CPP5s)

Adeno-associated viruses (AAVs) are a promising gene therapy technology, but major technical challenges remain. One problem is that commonly used AAVs have a low efficiency in penetrating the blood–brain barrier (BBB) and the blood–retina barrier (BRB). Consequently, gene delivery to the nervous sys...

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Principais autores:	Charles W. Guo, Anastasia Diener, Shigemi Matsuyama
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
coleção:	Pharmaceutics
Assuntos:	Cell-Penetrating Peptide (CPP) Cell-Penetrating Penta-peptide (CPP5) adenovirus vector (AAV) nanoparticle gene delivery blood–brain barrier
Acesso em linha:	https://www.mdpi.com/1999-4923/18/3/395
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