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Albumin-Keratin Casts Obstruct Renal Tubular and Vascular Lumens Following Kidney Ischemia

Introduction: We have recently reported that in ischemic acute kidney injury (AKI), red blood cell (RBC) trapping causes fluid extravasation from the congested capillary circulation and subsequent toxic injury to the surrounding tubules. The goal of this study was to identify the cause of the obstru...

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Autori principali: Martina Bryant, Olivia Boykin, Olivia Mosley, Angela Ajith, Oliver Oglesby, Konstantin Kurzin, Carlee Harris, Sadaf Husan, Daniela Dokam, Sarah R. McLarnon, Jingping Sun, Brendan Marshall, Amanda Barrett, Aaron Polichnowski, Wendy B. Bollag, David Mattson, Paul M. O’Connor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-04-01
Serie:Kidney International Reports
Soggetti:
acute kidney injury
casts
cytokeratin
ischemia-reperfusion
red blood cell trapping
Accesso online:http://www.sciencedirect.com/science/article/pii/S2468024926025878
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