Pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GC-2 in rats. Part 1. Single and multiple intravascular and extravascular administration. Testing the hypothesis of linearity of pharmacokinetics

The pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GC-2 in the rat blood plasma after different routes of administration was studied. The drug was administered at dose of 150 mg/kg by single and repeatedly. After single intravenous and intraperitoneal injection, GC-2 was detecte...

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Autores principales:	O. Yu. Kravtsova, O. G. Gribakina, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, P. Yu. Povarnina, V. P. Zherdev
Formato:	Artigo
Lenguaje:	Russo
Publicado:	LLC “Publisher OKI” 2023-11-01
Colección:	Фармакокинетика и Фармакодинамика
Materias:	nerve growth factor dimeric dipeptide mimetic gk-2 preclinical pharmacokinetics absolute bioavailability linearity of kinetics
Acceso en línea:	https://www.pharmacokinetica.ru/jour/article/view/377
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