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Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration

Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots in the endothelium are defined and how they are recognized by the leukocyte. Using lat...

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Sábháilte in:
Príomhchruthaitheoirí: Janine JG Arts, Eike K Mahlandt, Max LB Grönloh, Lilian Schimmel, Ivar Noordstra, Emma Gordon, Abraham CI van Steen, Simon Tol, Barbara Walzog, Jos van Rijssel, Martijn A Nolte, Marten Postma, Satya Khuon, John M Heddleston, Eric Wait, Teng Leong Chew, Mark Winter, Eloi Montanez, Joachim Goedhart, Jaap D van Buul
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2021-08-01
Sraith:eLife
Ábhair:
endothelium
Transmigration
protrusions
GTPase
actin
inflammation
Rochtain ar líne:https://elifesciences.org/articles/66074
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