Pterostilbene inhibits Gus-expressing microbiota that relieves irinotecan induced enterotoxicity in mice model
The clinical use of irinotecan (CPT-11), a first-line chemotherapeutic agent for solid tumors, is severely compromised by the side effect of diarrhea and enterotoxicity. This toxicity is largely driven by the reactivation of the metabolite SN-38G to cytotoxic SN-38 by bacterial β-glucuronidases (GUS...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2026-07-01
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| Schriftenreihe: | Journal of Agriculture and Food Research |
| Schlagworte: | |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2666154326004151 |
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