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Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model

Integrins are receptors that have been linked to various brain disorders, including Alzheimer's disease (AD), the most prevalent neurodegenerative disorder. While Integrin beta-3 (ITGB3) is known to participate in multiple cellular processes such as adhesion, migration, and signaling, its specific r...

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Principais autores: Mariia Ivanova, Irina Belaya, Nina Kucháriková, Izaque de Sousa Maciel, Liudmila Saveleva, Arto Alatalo, Ilona Juvonen, Navjot Thind, Clarisse Andrès, Riikka Lampinen, Sweelin Chew, Katja M. Kanninen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-02-01
Serier:Neurobiology of Disease
Fag:
Alzheimer's disease
Astrocyte
5xFAD mouse
ITGB3
GFAP
FAK
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996124000093
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