Highly conserved ion binding sites are not all functionally relevant in mouse KCC4
IntroductionThe potassium chloride cotransporter 4 (KCC4) is expressed in various tissues and plays an important role in distal renal acidification and hearing development. Although KCCs transport K+ and Cl− in a 1:1 stoichiometry, two Cl− coordination sites were indicated via cryo-electron microsco...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2025-03-01
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| Col·lecció: | Frontiers in Molecular Biosciences |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fmolb.2025.1556250/full |
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