Recombinant synthesis and immunological characterization of single-domain antibodies against botulinum neurotoxin serotype A and B

Nanobodies which are single-domain antibodies derived from the Variable Heavy domain of Heavy-chain-only antibodies (VHHs) found in camels and sharks, represent a novel approach for enhancing the detection and neutralization of food toxins. Botulinum neurotoxin (BoNT), a potent neurotoxin produced b...

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Hauptverfasser: Luong Trung Hieu, Bui Thi Thu Hoai, Phan Thi Thanh Thuy, Nguyen Le Duc Hai, Nguyen Thi Anh Nguyet, Pham Bao Yen, Nguyen Thi Hong Loan, Phan Tuan Nghia, Nguyen Thanh Trung, Le Phuong Linh, Trinh Van Toan, Le Thi Hong Nhung
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Institute for Food Control 2025-03-01
Schriftenreihe:Tạp chí Kiểm nghiệm và An toàn thực phẩm
Schlagworte:
nanobody
vhh
botulinum
food toxin
neutralization
recombinant protein
Online Zugang:https://vjfc.nifc.gov.vn/article?id=4454
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