Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation.

Mutation in the ubiquitously expressed cytoplasmic superoxide dismutase (SOD1) causes an inherited form of Amyotrophic Lateral Sclerosis (ALS). Mutant synthesis in motor neurons drives disease onset and early disease progression. Previous experimental studies have shown that spinal grafting of human...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Michael P Hefferan, Jan Galik, Osamu Kakinohana, Gabriela Sekerkova, Camila Santucci, Silvia Marsala, Roman Navarro, Marian Hruska-Plochan, Karl Johe, Eva Feldman, Don W Cleveland, Martin Marsala
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3423406?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!