Multifunctional Derivatives of Spiropyrrolidine Tethered Indeno-Quinoxaline Heterocyclic Hybrids as Potent Antimicrobial, Antioxidant and Antidiabetic Agents: Design, Synthesis, In Vitro and In Silico Approaches

To combat emerging antimicrobial-resistant microbes, there is an urgent need to develop new antimicrobials with better therapeutic profiles. For this, a series of 13 new spiropyrrolidine derivatives were designed, synthesized, characterized and evaluated for their in vitro antimicrobial, antioxidant...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Nouha Bouali, Manel Ben Hammouda, Iqrar Ahmad, Siwar Ghannay, Amira Thouri, Amal Dbeibia, Harun Patel, Walid Sabri Hamadou, Karim Hosni, Mejdi Snoussi, Mohd Adnan, Md Imtaiyaz Hassan, Emira Noumi, Kaïss Aouadi, Adel Kadri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-10-01
Colecção:	Molecules
Assuntos:	spiropyrrolidine derivatives antimicrobial antioxidant antidiabetic ADME molecular docking and dynamic simulation
Acesso em linha:	https://www.mdpi.com/1420-3049/27/21/7248
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!