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The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis

Abstract We have recently isolated, and determined the structure of a cycloheptapeptide, Mallotumide A from the Mallotus spodocarpus root extract. Here we reported the anti-cancer activity of Mallotumide A in highly invasive colon cancer, HCT116 and triple-negative breast cancer, MDA-MB-231 cell lin...

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Autori principali: Chayanee Laowittawat, Natthapat Sawektreeratana, Kanlaya Katewongsa, Pattaree Payomhom, Sakchai Hongthong, Vichai Reutrakul, Chutima Kuhakarn, Sarawut Jitrapakdee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-11-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-24547-x
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