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Practical considerations for choosing a mouse model of Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is behaviorally identified by progressive memory impairment and pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and neurodegeneration. Genetic mutations and risk factors have been identified that are either causal or modify t...

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Autors principals: Joanna L. Jankowsky, Hui Zheng
Format: Artigo
Idioma:Inglês
Publicat: BMC 2017-12-01
Col·lecció:Molecular Neurodegeneration
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Accés en línia:http://link.springer.com/article/10.1186/s13024-017-0231-7
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