A single acute alcohol intoxication before fracture insult causes long-term elevated systemic RANKL and OPG levels in young adult mice

Abstract Binge drinking is the most common form of alcohol abuse and 25–40% of orthopedic trauma patients are intoxicated upon admission. While alcohol consumption prolongs the healing time of bone fractures, the underlying mechanisms by which alcohol leads to this fracture healing disorder remain u...

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Autors principals:	Katrin Bundkirchen, Weikang Ye, Tianqi Zhang, Friederike Weidemann, Stefan Lienenklaus, Bastian Welke, Helen Rinderknecht, Borna Relja, Claudia Neunaber
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-07-01
Col·lecció:	Scientific Reports
Matèries:	Ethanol Bone regeneration Hemorrhagic shock µCT Histology Biomechanics
Accés en línia:	https://doi.org/10.1038/s41598-025-09240-3
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