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Serum levels of IgM to phosphatidylcholine predict the response of multiple sclerosis patients to natalizumab or IFN-β

Abstract We developed an ELISA assay demonstrating the high prevalence of serum IgM to phosphatidylcholine (IgM-PC) in the first stages of multiple sclerosis (MS). We aimed to analyze the role of serum IgM-PC as a biomarker of response to treatment. Paired serum samples from 95 MS patients were obta...

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Hlavní autoři: Úrsula Muñoz, Cristina Sebal, Esther Escudero, Elena Urcelay, Rafael Arroyo, Maria A. García-Martínez, Francisco J. Quintana, Roberto Álvarez-Lafuente, Maria Cruz Sádaba
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2022-08-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-022-16218-y
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