Changes of urinary immunity and microbiome after intravesical BCG therapy and their association with outcomes in NMIBC

Aim: Intravesical Bacillus Calmette–Guérin (BCG) is the standard therapy for non-muscle invasive bladder cancer (NMIBC); however, many patients experience recurrence or progression. We examined how urinary immune signals and the urinary microbiome change across BCG and are related to outcomes. Metho...

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Autori principali:	Yuki Oda, Makito Miyake, Nobutaka Nishimura, Takuto Shimizu, Takuya Owari, Kota Iida, Yasushi Nakai, Nobumichi Tanaka, Kiyohide Fujimoto
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Open Exploration Publishing Inc. 2026-04-01
Serie:	Exploration of Targeted Anti-tumor Therapy
Soggetti:	bacillus calmette–guérin (bcg) therapy non-muscle invasive bladder cancer urinary immune profiling urinary microbiome dynamics firmicutes/bacteroidetes ratio progression-free survival
Accesso online:	https://www.explorationpub.com/uploads/Article/A1002365/1002365.pdf
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