Development of a targeted flip-in system in avian DT40 cells.
Gene-targeting to create null mutants or designed-point mutants is a powerful tool for the molecular dissection of complex phenotypes involving DNA repair, signal transduction, and metabolism. Because gene-targeting is critically impaired in mutants exhibiting attenuated homologous recombination (HR...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2015-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC4370768?pdf=render |
| Oznake: |
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