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mRNA:guanine-<it>N</it>7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

<p>Abstract</p> <p>Background</p> <p>The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors. There is a large body of experimental data on viral and cellular meth...

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Principais autores: Radlinska Monika, Feder Marcin, Bujnicki Janusz M, Rychlewski Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2001-06-01
coleção:BMC Bioinformatics
Acesso em linha:http://www.biomedcentral.com/1471-2105/2/2
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