hUCMSCs restore ovarian function via angiopoietin 1/2 rebalance in POI rats

Abstract Background Premature ovarian insufficiency (POI) is often iatrogenic and the therapeutic potential of human umbilical cord derived mesenchymal stem cells (hUCMSCs) remain incompletely defined. This study aimed to evaluate the effects and underlying mechanism of hUCMSCs on ovarian function i...

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Detalles Bibliográficos

Principais autores:	Qianqian Luo, Chengen Liu, Yongtao Su, Ranran Liu, Zhonglin Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-11-01
Series:	Journal of Ovarian Research
Assuntos:	Premature ovarian insufficiency Human umbilical cord mesenchymal stem cells Rat ovarian microvascular endothelial cells Angiopoietin 1 Angiopoietin 2
Acceso en liña:	https://doi.org/10.1186/s13048-025-01856-3
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