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Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Abstract Current pharmacotherapies for post‐traumatic stress disorder (PTSD) are limited by delayed onset and side effects. Despite ketamine exhibiting rapid relief of the core symptoms of PTSD, its clinical efficacy varies considerably depending on the timing of drug delivery. However, the underlyi...

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Furkejuvvon:
Váldodahkkit: Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2025-12-01
Ráidu:Advanced Science
Fáttát:
PTSD
S‐ketamine
TI‐NIBS
VTA dopamine
Liŋkkat:https://doi.org/10.1002/advs.202500805
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