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Genetic analysis of ligation-induced neointima formation in an F2 intercross of C57BL/6 and FVB/N inbred mouse strains.

Proliferation and migration of vascular smooth muscle cells (SMCs) are central for arterial diseases including atherosclerosis and restenosis. We hypothesized that the underlying mechanisms may be modeled by carotid ligation in mice. In FVB/N inbred mice, ligation leads to abundant neointima formati...

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Autors principals: Caroline Östergren, Jeong Shim, Jens Vinther Larsen, Lars Bo Nielsen, Jacob F Bentzon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4395357?pdf=render
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