Á lódáil...

Hiding in plain sight: structure and sequence analysis reveals the importance of the antibody DE loop for antibody-antigen binding

Antibody variable domains contain “complementarity-determining regions” (CDRs), the loops that form the antigen binding site. CDRs1-3 are recognized as the canonical CDRs. However, a fourth loop sits adjacent to CDR1 and CDR2 and joins the D and E strands on the antibody v-type fold. This “DE loop”...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Simon P. Kelow, Jared Adolf-Bryfogle, Roland L. Dunbrack
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis Group 2020-01-01
Sraith:mAbs
Ábhair:
Rochtain Ar Líne:https://www.tandfonline.com/doi/10.1080/19420862.2020.1840005
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!