Liver specification of human iPSC-derived endothelial cells transplanted into mouse liver

Background & Aims: Liver sinusoidal endothelial cells (LSECs) are important in liver development, regeneration, and pathophysiology, but the differentiation process underlying their tissue-specific phenotype is poorly understood and difficult to study because primary human cells are scarce. The...

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Principais autores:	Kiryu K. Yap, Jan Schröder, Yi-Wen Gerrand, Aleksandar Dobric, Anne M. Kong, Adrian M. Fox, Brett Knowles, Simon W. Banting, Andrew G. Elefanty, Eduoard G. Stanley, George C. Yeoh, Glen P. Lockwood, Victoria C. Cogger, Wayne A. Morrison, Jose M. Polo, Geraldine M. Mitchell
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-05-01
Series:	JHEP Reports
Assuntos:	Liver Liver sinusoidal endothelial cells Tissue specification Induced pluripotent stem cells Cell transplantation
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2589555924000247
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