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Screening of selective histone deacetylase inhibitors by proteochemometric modeling

<p>Abstract</p> <p>Background</p> <p>Histone deacetylase (HDAC) is a novel target for the treatment of cancer and it can be classified into three classes, i.e., classes I, II, and IV. The inhibitors selectively targeting individual HDAC have been proved to be the better candidate antitumor drugs. To...

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Bibliografische Detailangaben
Hauptverfasser: Wu Dingfeng, Huang Qi, Zhang Yida, Zhang Qingchen, Liu Qi, Gao Jun, Cao Zhiwei, Zhu Ruixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2012-08-01
Schriftenreihe:BMC Bioinformatics
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Online-Zugang:http://www.biomedcentral.com/1471-2105/13/212
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