Koumine exerts its anti-colorectal cancer effects by disrupting the interaction between HSP90 and CDC37, thereby downregulating downstream signaling pathways
BackgroundKoumine, a principal bioactive alkaloid derived from the traditional Chinese herb Gelsemium elegans, has demonstrated broad cytotoxic activity against various cancer cell lines. However, its specific anti-tumor efficacy and underlying molecular mechanisms in colorectal cancer (CRC) remain...
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| Huvudupphov: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Frontiers Media S.A.
2026-01-01
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| Serie: | Frontiers in Oncology |
| Ämnen: | |
| Länkar: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1687690/full |
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