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DNA glycosylases Ogg1 and Mutyh influence gene expression of PRC2 targets associated with cognition

Abstract Base excision repair, initiated by DNA glycosylases, preserves genomic integrity by removing damaged bases. DNA glycosylases Ogg1 and Mutyh were shown to alter the hippocampal transcriptome independently of DNA damage repair. However, the role of DNA glycosylases as transcriptional regulato...

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主要な著者: Andreas Abentung, Teri Sakshaug, Rabina Dumaru, Nina-Beate Liabakk, Mingyi Yang, Junbai Wang, Magnar Bjørås, Katja Scheffler
フォーマット: Artigo
言語:Inglês
出版事項: Springer 2025-08-01
シリーズ:Cellular and Molecular Life Sciences
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オンライン・アクセス:https://doi.org/10.1007/s00018-025-05730-9
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