Biosynthesis of thiocarboxylic acid-containing natural products

Thioplatensimycin (thioPTM) and thioplatencin (thioPTN) are recently discovered thiocarboxylic acid congeners of the antibacterial compounds PTM and PTN. Here, the authors identify a thioacid cassette encoding PtmA3 and PtmU4 that are responsible for carboxylate activation and sulfur transfer, respe...

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Autors principals:	Liao-Bin Dong, Jeffrey D. Rudolf, Dingding Kang, Nan Wang, Cyndi Qixin He, Youchao Deng, Yong Huang, K. N. Houk, Yanwen Duan, Ben Shen
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2018-06-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-018-04747-y
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