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Understanding the Hysteresis Loop Conundrum in Pharmacokinetic / Pharmacodynamic Relationships

Hysteresis loops are phenomena that sometimes are encountered in the analysis of pharmacokinetic and pharmacodynamic relationships spanning from pre-clinical to clinical studies. When hysteresis occurs it provides insight into the complexity of drug action and disposition that can be encountered. Hy...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Christopher Louizos, Jaime A Yáñez, M Laird Forrest, Neal M Davies
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014-03-01
Schriftenreihe:Journal of Pharmacy & Pharmaceutical Sciences
Online-Zugang:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/21028
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