Next generation of immune checkpoint therapy in cancer: new developments and challenges
Abstract Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response. In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act by blocking or stimula...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2018-03-01
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| Schriftenreihe: | Journal of Hematology & Oncology |
| Schlagworte: | |
| Online-Zugang: | http://link.springer.com/article/10.1186/s13045-018-0582-8 |
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