Swine GBP1 restricts PDCoV replication via disrupting the replication and transcription complex formation

ABSTRACT Porcine deltacoronavirus (PDCoV) has been prevalent worldwide for over a decade, causing considerable economic damage to the pig industry and posing a potential threat to public biosecurity. In this study, we found that one of the interferon-stimulated genes (ISGs), swine guanylate-binding...

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Hauptverfasser:	Kunli Zhang, Sutian Wang, Xintong Kang, Fei Li, Ziqiao Zhao, Wuri Nile, Chunhong Zhang, Haiyan Shen, Shouwen Du, Huahua Kang, Mingfei Sun, Zhicheng Liu, Jianfeng Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2026-05-01
Schriftenreihe:	Journal of Virology
Schlagworte:	porcine deltacoronavirus (PDCoV) swine guanylate-binding protein 1 (sGBP1) replication and transcription complex (RTC) non-structural protein 8 (NSP8) antiviral responses
Online-Zugang:	https://journals.asm.org/doi/10.1128/jvi.00207-26
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