The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence in Saccharomyces cerevisiae

The rate and regulation of mRNA decay are major elements in the proper control of gene expression. Edc3 and Lsm4 are two decapping activator proteins that have previously been shown to function in the assembly of RNA granules termed P bodies. Here, we show that deletion of edc3, when combined with a...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Susanne Huch, Maren Müller, Mridula Muppavarapu, Jessie Gommlich, Vidya Balagopal, Tracy Nissan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Company of Biologists 2016-10-01
coleção:	Biology Open
Assuntos:	P bodies Deadenylation Exosome mRNA decapping mRNA decay mRNA stability
Acesso em linha:	http://bio.biologists.org/content/5/10/1388
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!