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SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs.

Stem cells are defined by their capacities to self-renew and generate progeny of multiple lineages. The transcription factor SOX2 has key roles in the regulation of stem cell characteristics, but whether SOX2 achieves these functions through similar mechanisms in distinct stem cell populations is no...

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Autori principali: Daniel W Hagey, Susanne Klum, Idha Kurtsdotter, Cecile Zaouter, Danijal Topcic, Olov Andersson, Maria Bergsland, Jonas Muhr
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-02-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC5825159?pdf=render
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