Innate Immune-Directed NF-κB Signaling Requires Site-Specific NEMO Ubiquitination

While the I kappa kinase (IKK) scaffolding protein NF-κB essential modulator (NEMO) binds to polyubiquitin chains to transmit inflammatory signals, NEMO itself is also ubiquitinated in response to a variety of inflammatory agonists. Although there have been hints that polyubiquitination of NEMO is e...

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Bibliografiske detaljer

Principais autores:	Janice C. Jun, Sylvia Kertesy, Mark B. Jones, Jill M. Marinis, Brian A. Cobb, Justine T. Tigno-Aranjuez, Derek W. Abbott
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2013-07-01
Serier:	Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124713003288
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