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NSUN2 restrains gastric cancer cell apoptosis and ferroptosis by promoting the m5C modification of EPYC

Abstract Background Epiphycan (EPYC) has been confirmed to play an oncogenic role in many cancers. However, its role and mechanism in gastric cancer (GC) progression has not been explored. Methods The levels of EPYC and NOP2/Sun domain 2 (NSUN2) were detected by qRT-PCR and western blot. Cell prolif...

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Autori principali: Lei Wu, Boxuan Chen, Si Cheng, Xiaofeng Fang, Fen Zhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-01-01
Serie:Hereditas
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Accesso online:https://doi.org/10.1186/s41065-025-00626-x
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