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Unc-51-like kinase 1 (ULK1) regulates bacterial ubiquitylation and p62 recruitment during xenophagic clearance of Listeria monocytogenes

ABSTRACT Autophagy is an essential cellular homeostatic process that also serves as an innate immune mechanism against intracellular bacterial pathogens through a highly selective form of autophagy known as xenophagy. Despite advances in understanding how bacteria are targeted for autophagic degrada...

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Principais autores: J. S. Ribeiro, M. S. Siqueira, T. S. M. Farias, T. D. P. Spinasse, P. L. O. Correia, R. M. Ribeiro, F. M. Bastos de Oliveira, L. A. M. Carneiro, L. H. Travassos
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-09-01
Serier:mSphere
Fag:
xenophagy
autophagy
ULK1
p62
ubiquitination
Listeria monocytogenes
Online adgang:https://journals.asm.org/doi/10.1128/msphere.00308-25
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