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Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases

The trypsin-like proteases (TLPs) play widespread and diverse roles, in a host of physiological and pathological processes including clot dissolution, extracellular matrix remodelling, infection, angiogenesis, wound healing and tumour invasion/metastasis. Moreover, these enzymes are involved in the...

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Principais autores: Timothy E. G. Ferguson, James A. Reihill, S. Lorraine Martin, Brian Walker
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Chemistry
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fchem.2022.782608/full
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