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Confidence: a web app for cross-platform differential gene expression analysis, gene scoring, and enrichment analysis

Abstract RNA-seq quantifies the abundance of transcripts within a biological sample and performs differential analysis between different conditions to reveal regulated gene signatures. Three challenges exist: (1) different analytical packages can often report different expression patterns and false-...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Abhishek Shastry, Benjamin P. Ott, Tanvi Nandani, Alex Paterson, Matt Simpson, Kimberly J. Dunham-Snary, Charles C. T. Hindmarch
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-04-01
Schriftenreihe:Scientific Reports
Schlagworte:
RNA sequencing
Gene expression omnibus
DESeq2
EdgeR
NOISEQ
Limma
Online-Zugang:https://doi.org/10.1038/s41598-026-50527-w
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