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The Dynamic Instability of the Aneuploid Genome

Proper partitioning of replicated sister chromatids at each mitosis is crucial for maintaining cell homeostasis. Errors in this process lead to aneuploidy, a condition in which daughter cells harbor genome imbalances. Importantly, aneuploid cells often experience DNA damage, which in turn could driv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lorenza Garribba, Stefano Santaguida
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2022-02-01
Cyfres:Frontiers in Cell and Developmental Biology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fcell.2022.838928/full
Tagiau: Ychwanegu Tag
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