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Repurposing epetraborole to combat Neisseria gonorrhoeae and Chlamydia trachomatis infections

ABSTRACT Neisseria gonorrhoeae and Chlamydia trachomatis are the most common bacterial sexually transmitted infections. The World Health Organization (WHO) estimates that there were approximately 211 million cases of chlamydia and gonorrhea in 2020. Currently, no single drug is effective against bot...

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Furkejuvvon:
Váldodahkkit: Abdallah S. Abdelsattar, Babatomiwa Kikiowo, Nader S. Abutaleb, Autumn S. Dove, Mohamed N. Seleem
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: ASM 2026-01-01
Ráidu:Antimicrobial Agents and Chemotherapy
Fáttát:
epetraborole
sexually transmitted infections
antibacterial resistance
inclusion bodies
bacterial intracellular clearance
In vivo mouse model
Liŋkkat:https://journals.asm.org/doi/10.1128/aac.01445-25
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